Prothena Corporation plc - Ordinary Shares (PRTA)
14.23
-0.47 (-3.20%)
Prothena Corp is a biotechnology company focused on the discovery and development of innovative therapies to treat diseases caused by protein misfolding and aggregation
The company specializes in the research and development of monoclonal antibodies and other advanced treatments aimed at targeting neurodegenerative diseases, including Alzheimer's and Parkinson's. Through its proprietary platform, Prothena aims to address significant unmet medical needs by advancing its drug candidates through clinical trials, ultimately seeking to enhance the quality of life for patients suffering from these challenging conditions.
Prothena Announces Board of Directors Update
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that Oleg Nodelman will step down from Prothena’s Board of Directors to create time to focus on existing and new endeavors. During his five-year tenure, Mr. Nodelman played a pivotal role in which he made significant contributions to the Company’s current strategy.
By Prothena Corporation plc · Via Business Wire · December 30, 2024
Roche’s Phase IIb Study of Prasinezumab Missed Primary Endpoint, But Suggests Possible Clinical Benefit in Early-Stage Parkinson’s Disease
Prothena Corporation plc (NASDAQPRTA), today announced results from the Phase IIb PADOVA study conducted by partner Roche investigating prasinezumab in 586 people with early-stage Parkinson’s disease, treated for a minimum of 18 months while on stable symptomatic treatment. Prasinezumab showed potential clinical effect in the primary endpoint of time to confirmed motor progression with a HR=0.84 [0.69-1.01] and p=0.0657. The effect of prasinezumab was more pronounced in a pre-specified analysis in the population treated with levodopa (75% of participants), HR=0.79 [0.63-0.99] and nominal p=0.0431. Pre-specified supplementary covariate-adjusted* analyses of these endpoints demonstrated nominally significant effects on the primary endpoint (HR=0.81 [0.67-0.98]; nominal p=0.0334) and in the levodopa subgroup (HR=0.76 [0.61-0.95]; nominal p=0.0175). Consistent positive trends across multiple secondary and exploratory endpoints were also observed. Prasinezumab continues to be well tolerated and no new safety signals were observed in the study.
By Prothena Corporation plc · Via Business Wire · December 19, 2024
Prothena Reports Third Quarter 2024 Financial Results and Business Highlights
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today reported financial results for the third quarter and first nine months of 2024 and provided business highlights.
By Prothena Corporation plc · Via Business Wire · November 12, 2024
Prothena to Report Third Quarter 2024 Financial Results on November 12
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that it will report its third quarter and first nine months of 2024 financial results on Tuesday, November 12, 2024, after the close of the U.S. financial markets.
By Prothena Corporation plc · Via Business Wire · November 5, 2024
Prothena Announces Leadership Team Updates
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that Chad Swanson, Ph.D., has been appointed Chief Development Officer and will assume leadership of clinical development and medical functions. Chad will join Prothena’s executive leadership team and will report to Gene Kinney, Ph.D., President and Chief Executive Officer. Hideki Garren, M.D., Ph.D., will pursue an opportunity at a large pharmaceutical company to lead a global product development division. Prothena will initiate a search for a world-class healthcare leader as our next Chief Medical Officer.
By Prothena Corporation plc · Via Business Wire · September 27, 2024
Prothena to Participate in Upcoming Healthcare Conferences
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that members of its senior management team will participate in the following upcoming investor conferences:
By Prothena Corporation plc · Via Business Wire · August 29, 2024
Prothena Reports Second Quarter 2024 Financial Results and Business Highlights
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today reported financial results for the second quarter and first six months of 2024 and provided business highlights.
By Prothena Corporation plc · Via Business Wire · August 8, 2024
Prothena to Report Second Quarter 2024 Financial Results on August 8
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that it will report its second quarter and first six months of 2024 financial results on Thursday, August 8, 2024, after the close of the U.S. financial markets.
By Prothena Corporation plc · Via Business Wire · August 1, 2024
Prothena Announces Bristol Myers Squibb Opt-in for Exclusive Global License for PRX019, the Second Program from Global Neuroscience Research and Development Collaboration
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that Bristol Myers Squibb obtained the exclusive global license for PRX019 and will pay Prothena $80 million.
By Prothena Corporation plc · Via Business Wire · May 28, 2024
Prothena Reports First Quarter 2024 Financial Results and Business Highlights
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today reported financial results for the first quarter of 2024 and provided business highlights.
By Prothena Corporation plc · Via Business Wire · May 8, 2024
Prothena to Report First Quarter 2024 Financial Results on May 8
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that it will report its first quarter 2024 financial results on Wednesday, May 8, 2024, after the close of the U.S. financial markets.
By Prothena Corporation plc · Via Business Wire · May 1, 2024
Prothena Announces Review on Birtamimab Mechanism of Action and Pharmacological Characteristics Published in Leukemia & Lymphoma
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced the publication related to the mechanism of action, pharmacological characteristics, and clinical utility of birtamimab, a potential best-in-class anti-amyloid treatment for AL amyloidosis. The publication can be found in the latest issue of Leukemia & Lymphoma, an international peer-reviewed journal that publishes research on all aspects of hematological malignancies.
By Prothena Corporation plc · Via Business Wire · April 15, 2024
Prothena to Participate in Upcoming Healthcare Conferences
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that members of its senior management team will participate in the following upcoming investor conferences:
By Prothena Corporation plc · Via Business Wire · March 5, 2024
Prothena Appoints David Ford to Newly Created Chief People Officer Position
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that it has named David Ford to a newly created position of Chief People Officer, reporting to Prothena President and Chief Executive Officer Gene Kinney, PhD. In this role, Mr. Ford will be responsible for people, culture, and human resources strategy to drive the company’s vision and overall growth strategy.
By Prothena Corporation plc · Via Business Wire · March 4, 2024
Prothena Announces Appointment of Daniel G. Welch as Director and Chair Designate
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, announced today the appointment of Daniel G. Welch to its Board of Directors as an independent director and Chair Designate following a comprehensive search process in connection with the board’s regular succession planning.
By Prothena Corporation plc · Via Business Wire · February 21, 2024
Prothena Reports Fourth Quarter and Full Year 2023 Financial Results, and Provides Financial Guidance and Business Highlights
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today reported financial results for the fourth quarter and full year 2023. In addition, the Company provided 2024 financial guidance and business highlights.
By Prothena Corporation plc · Via Business Wire · February 15, 2024
Prothena to Report Fourth Quarter and Full Year 2023 Financial Results on February 15, 2024
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that it will report its fourth quarter and full year 2023 financial results on Thursday, February 15, 2024 after the close of the U.S. financial markets. The announcement will be followed by a live audio conference call at 4:30 PM ET.
By Prothena Corporation plc · Via Business Wire · February 8, 2024
Prothena Provides Updates on PRX012, PRX123, Birtamimab and Portfolio Programs
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, provided a business update on portfolio programs.
By Prothena Corporation plc · Via Business Wire · January 8, 2024
Prothena Reports Third Quarter 2023 Financial Results and Business Highlights
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today reported financial results for the third quarter and first nine months of 2023 and provided business highlights.
By Prothena Corporation plc · Via Business Wire · November 2, 2023
Prothena to Report Third Quarter 2023 Financial Results on November 2
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that it will report its third quarter and first nine months of 2023 financial results on Thursday, November 2, 2023 after the close of the U.S. financial markets.
By Prothena Corporation plc · Via Business Wire · October 26, 2023
Prothena to Participate in Upcoming Healthcare Conferences
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that members of its senior management team will participate in the following upcoming investor conferences:
By Prothena Corporation plc · Via Business Wire · August 31, 2023
Prothena Reports Second Quarter 2023 Financial Results and Business Highlights
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today reported financial results for the second quarter and first six months of 2023 and provided business highlights.
By Prothena Corporation plc · Via Business Wire · August 3, 2023
Prothena to Report Second Quarter 2023 Financial Results on August 3
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced that it will report its second quarter and first six months of 2023 financial results on Thursday, August 3, 2023 after the close of the U.S. financial markets.
By Prothena Corporation plc · Via Business Wire · July 27, 2023
Prothena Presents New Research in the Treatment of Alzheimer’s Disease at Alzheimer’s Association International Conference® 2023 (AAIC®)
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today shared data on three investigational product programs for the treatment and prevention of Alzheimer’s disease, PRX005, PRX012 and PRX123, at the Alzheimer’s Association International Conference® 2023 (AAIC®) being held July 16-20, 2023 in Amsterdam, Netherlands and virtually.
By Prothena Corporation plc · Via Business Wire · July 17, 2023
Prothena to Present New Data from Alzheimer’s Disease Programs at Alzheimer’s Association International Conference® 2023 (AAIC®)
Prothena Corporation plc (NASDAQPRTA), a late-stage clinical biotechnology company with a robust pipeline of investigational therapeutics built on protein dysregulation expertise, today announced participation in the Alzheimer’s Association International Conference® 2023 (AAIC®) being held July 16-20, 2023 in Amsterdam, Netherlands and virtually. Participation includes three posters highlighting the company’s next generation therapies for Alzheimer’s disease and a Prothena sponsored symposium.
By Prothena Corporation plc · Via Business Wire · July 11, 2023