On December 2, 2025, BIOHONG Group successfully held the “2026 Global Release Conference on Dermal Targeting Specific Supramolecular Technology,” unveiling three major innovations—the Pan-Ecological PDRN System, the Pan-Ecological Bio-Vesicles System, and the AISSM™ Intelligent Raw-Material Research Platform. Embracing the AI-driven era, BIOHONG Group is transforming industry-wide technological shifts into new development opportunities and building an intelligent technology platform that expands the boundaries of skincare raw-material innovation.
Using “AI + R&D” as the Key to Unlock the Intelligent Era of PDRN Precision Skincare
As a pioneer in merging regenerative medicine with skincare technology, BIOHONG Group has cultivated deep expertise in dermatology and regenerative medicine for over 20 years. To address the long cycles and high costs of traditional trial‑and‑error R&D, BIOHONG has launched three major innovations: the Pan-Ecological PDRN System, the Pan-Ecological Bio‑Vesicles System, and the AISSM™ Intelligent Raw‑Material Research Platform.
These innovations empower supramolecular microsphere technology, building a precise, intelligent anti‑aging matrix and setting a new paradigm for data‑driven precision repair.
From R&D Efficiency to Industrial Transformation: Nucleic‑Acid Technology Unlocks Bidirectional Value
The Pan-Ecological PDRN System, Pan-Ecological Bio‑Vesicles, and AISSM™ Platform provide a closed‑loop solution covering R&D, production, and application—driving the industry from experience‑based practices to data‑driven and standardized development.
1. Pan-Ecological PDRN — Expanding the PDRN Landscape & Reinforcing Targeted Efficacy
As precise targeting becomes the core trend of efficacy skincare, PDRN acts as a “golden ingredient” driving system‑level upgrades. BIOHONG innovates PDRN across animal, plant, probiotic, and synthetic sources—achieving Pan-Ecological coverage.
Different PDRN sources offer unique targeted benefits, helping brands differentiate through precise ingredient pairing. Through microbial metabolic‑pathway engineering, scarce fish‑derived PDRN is transformed into a stable, scalable, high‑purity bio-manufactured system.
Supported by AISSM™, fragmented data is unified into a scientific database. BIOHONG also led the creation of China’s General Requirements for Cosmetic‑Grade PDRN Testing, establishing standardized quality control from raw materials to finished products and advancing the shift from “ingredient marketing” to “scientific skincare.”
2. Pan-Ecological Bio‑Vesicles — Multi‑Source Innovation Breaking PDRN Application Barriers
As a national leader in exosome technology, BIOHONG developed the Pan-Ecological Bio‑Vesicle System and achieved breakthroughs in large‑scale extraction and application. In 2025, the company released industry standards, secured national invention patents, and published key findings in the high‑impact journal Bioactive Materials.
Built on the JEVexo® platform, the system integrates animal, plant, and probiotic vesicles and advances engineered exosome technologies. Through vesicle‑based encapsulation, it overcomes the delivery barriers of PDRN and creates a synergistic “1 + 1 > 2” molecular effect. This expands ingredient boundaries and deepens biotech–beauty integration.
3. AISSM™ Intelligent Raw‑Material Research Platform — Using AI to Reshape PDRN R&D
AISSM™ is an AI supramolecular‑assembly platform integrating multi‑dimensional databases and self‑developed algorithms. It transforms molecular self‑assembly from complex, experience‑dependent experiments into data‑driven intelligent decision‑making.
The platform enables computable, predictable, and optimizable ingredients, significantly enhancing R&D reproducibility and setting the foundation for measurable efficacy in the AI‑driven precision‑microsphere era.
Technology‑Driven Innovation Empowering Brand‑Value Growth
BIOHONG has achieved industrial breakthroughs in Full‑Ecology PDRN and Bio‑Vesicles and forged strategic partnerships with brands such as Hanhoo, SUKII, OSM, HAIROLOGY, and Nox Bellcow.
Multiple BIOHONG‑supported brands—including Jumiya, FULCYTO.amie, TimePoem, and HAIREGEN—have transformed these technologies into strong product competitiveness.
Jumiya stood out with a feature collaboration with Austin Li and China Women’s News titled “When the People Who Make Skin Create Skincare.” During Double 11, the brand achieved 147% YoY GMV growth, ranking among Tmall’s Top 4 emerging beauty brands.
Leveraging BIOHONG’s Pan-Ecological PDRN matrix and synthetic‑biology innovation, Jumiya launched the breakthrough PDRN Ultra‑Glow Hydro Mask featuring Mito‑S‑PDRN and Spherical Peptide technology.
Co‑Creating Knowledge and Exploring New Heights in Nucleic‑Acid Skincare
At the 2026 Global Forum on Supramolecular Targeting Technologies, experts in regenerative medicine and beauty‑industry leaders discussed innovations in nucleic‑acid science, R&D barriers, and industrial‑ecosystem advancement—mapping a new pathway for the future of high‑tech skincare.
Deepening Technological Implementation & Driving High‑Energy Industry Growth
The 2026 global conference marks a milestone for BIOHONG and signals China’s progression into intelligent, scientific skincare development.
The launch of Pan-Ecological PDRN, Pan-Ecological Bio‑Vesicles, and AISSM™ sets a new benchmark for ingredient innovation, AI empowerment, and collaborative ecosystems. Looking ahead, BIOHONG will continue strengthening China’s global competitiveness and driving high‑quality development, writing a new chapter of “China‑Made Intelligence” in the global skincare landscape.
Media Contact
Company Name: Biohong Group
Contact Person: She Yaoyao
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Country: China
Website: http://www.biohong.com/